What is Optimal Selection™?

Optimal Selection™ provides breeders with the most comprehensive test of its kind, to promote "smarter breeding through genetics". This test is a screening tool for genetic conditions related to drug sensitivities, vision, weight, mobility, and more, with 200+ health tests, including 40+ traits (coat colors, coat types, and morphology) and the genetic diversity of the tested dog. The tests included are:

  • 2,8-dihydroxyadenine (DHA) Urolithiasis
  • Acral Mutilation Syndrome
  • Acute Respiratory Distress Syndrome
  • Alaskan Husky Encephalopathy
  • Alexander Disease
  • Amelogenesis Imperfecta
  • Bandera's Neonatal Ataxia
  • Benign Familial Juvenile Epilepsy
  • Canine Leukocyte Adhesion Deficiency (CLAD), type III
  • Canine Multifocal Retinopathy 1
  • Canine Multifocal Retinopathy 2
  • Canine Multifocal Retinopathy 3
  • Canine Scott Syndrome
  • Centronuclear Myopathy (Discovered in the Great Dane)
  • Centronuclear Myopathy (Discovered in the Labrador Retriever)
  • Cerebellar Ataxia
  • Cerebellar Cortical Degeneration
  • Cerebellar Hypoplasia
  • Cerebral Dysfunction
  • Chondrodysplasia
  • Cleft Lip & Palate with Syndactyly
  • Cleft Palate
  • Collie Eye Anomaly (CEA)
  • Complement 3 Deficiency
  • Cone Degeneration (Discovered in the Alaskan Malamute)
  • Cone Degeneration (Discovered in the German Shepherd Dog)
  • Cone Degeneration (Discovered in the German Shorthaired Pointer)
  • Cone-Rod Dystrophy
  • Cone-Rod Dystrophy 1
  • Cone-Rod Dystrophy 2
  • Congenital Dyshormonogenic Hypothyroidism with Goiter (Discovered in the Shih Tzu)
  • Congenital Hypothyroidism (Discovered in the Tenterfield Terrier)
  • Congenital Hypothyroidism (Discovered in the Toy Fox and Rat Terrier)
  • Congenital Myasthenic Syndrome (Discovered in the Golden Retriever)
  • Congenital Myasthenic Syndrome (Discovered in the Jack Russell Terrier)
  • Congenital Myasthenic Syndrome (Discovered in the Labrador Retriever)
  • Congenital Myasthenic Syndrome (Discovered in the Old Danish Pointing Dog)
  • Congenital Stationary Night Blindness (CSNB)
  • Craniomandibular Osteopathy
  • Cystic Renal Dysplasia and Hepatic Fibrosis
  • Cystinuria Type I-A
  • Cystinuria Type II-A
  • Deafness and Vestibular Dysfunction (Discovered in Doberman Pinscher)
  • Degenerative Myelopathy
  • Demyelinating Neuropathy
  • Dental Hypomineralization
  • Dilated Cardiomyopathy
  • Dominant Progressive Retinal Atrophy
  • Dystrophic Epidermolysis Bullosa (Discovered in the Central Asian Ovcharka)
  • Dystrophic Epidermolysis Bullosa (Discovered in the Golden Retriever)
  • Early Adult Onset Deafness For Border Collies only (Linkage test)
  • Early Retinal Degeneration (Discovered in the Norwegian Elkhound)
  • Early-onset PRA (Discovered in the Portuguese Water Dog)
  • Early-Onset Progressive Polyneuropathy (Discovered in the Alaskan Malamute)
  • Early-Onset Progressive Polyneuropathy (Discovered in the Greyhound)
  • Enamel Hypoplasia (Discovered in the Parson Russell Terrier)
  • Epidermolytic Hyperkeratosis
  • Episodic Falling Syndrome
  • Exercise-Induced Collapse
  • Factor VII Deficiency
  • Factor XI Deficiency
  • Fanconi Syndrome
  • Fetal Onset Neuroaxonal Dystrophy
  • Focal Non-Epidermolytic Palmoplantar Keratoderma
  • Generalized Progressive Retinal Atrophy (Discovered in the Schapendoes)
  • Glanzmann Thrombasthenia Type I
  • Glanzmann Thrombasthenia Type I (Discovered in Great Pyrenees)
  • Globoid Cell Leukodystrophy (Discovered in Terriers)
  • Globoid Cell Leukodystrophy (Discovered in the Irish Setter)
  • Glycogen Storage Disease Type Ia
  • Glycogen Storage Disease Type IIIa, (GSD IIIa)
  • GM1 Gangliosidosis (Discovered in the Portuguese Water Dog)
  • GM1 Gangliosidosis (Discovered in the Shiba)
  • GM2 Gangliosidosis (Discovered in the Japanese Chin)
  • GM2 Gangliosidosis (Discovered in the Toy Poodle)
  • Goniodysgenesis and Glaucoma (Discovered in the Border Collie)
  • Hemophilia A (Discovered in Old English Sheepdog)
  • Hemophilia A (Discovered in the Boxer)
  • Hemophilia A (Discovered in the German Shepherd Dog - Variant 1)
  • Hemophilia A (Discovered in the German Shepherd Dog - Variant 2)
  • Hemophilia A (Discovered in the Havanese)
  • Hemophilia B
  • Hemophilia B (Discovered in the Airedale Terrier)
  • Hemophilia B (Discovered in the Lhasa Apso)
  • Hereditary Ataxia (Discovered in the Norwegian Buhund)
  • Hereditary Elliptocytosis
  • Hereditary Footpad Hyperkeratosis
  • Hereditary Nasal Parakeratosis (Discovered in the Greyhound)
  • Hereditary Nasal Parakeratosis (Discovered in the Labrador Retriever)
  • Hereditary Vitamin D-Resistant Rickets Type II
  • Hyperekplexia or Startle Disease
  • Hyperuricosuria
  • Hypocatalasia
  • Hypomyelination
  • Hypophosphatemia
  • Ichthyosis (Discovered in the American Bulldog)
  • Ichthyosis (Discovered in the Great Dane)
  • Intestinal Cobalamin Malabsorption (Discovered in the Beagle)
  • Intestinal Cobalamin Malabsorption (Discovered in the Border Collie)
  • Intestinal Cobalamin Malabsorption (Discovered in the Komondor)
  • Juvenile Encephalopathy (Discovered in the Parson Russell Terrier)
  • Juvenile Laryngeal Paralysis and Polyneuropathy
  • Juvenile Myoclonic Epilepsy
  • L-2-Hydroxyglutaric Aciduria
  • L-2-Hydroxyglutaric Aciduria (Discovered in the Westie)
  • Lagotto Storage Disease
  • Lamellar Ichthyosis
  • Lethal Acrodermatitis (Discovered in the Bull Terrier)
  • Ligneous Membranitis
  • Lung Developmental Disease (Discovered in the Airedale Terrier)
  • Macrothrombocytopenia
  • May-Hegglin Anomaly
  • MDR1 Medication Sensitivity
  • Microphthalmia (Discovered in the Soft-Coated Wheaten Terrier)
  • Mucopolysaccharidosis Type IIIA (Discovered in the Dachshund)
  • Mucopolysaccharidosis Type IIIA (Discovered in the New Zealand Huntaway)
  • Mucopolysaccharidosis Type VII (Discovered in the Brazilian Terrier)
  • Mucopolysaccharidosis Type VII (Discovered in the German Shepherd Dog)
  • Muscular Dystrophy (Discovered in the Cavalier King Charles Spaniel)
  • Muscular Dystrophy (Discovered in the Golden Retriever)
  • Muscular Dystrophy (Discovered in the Landseer)
  • Muscular Dystrophy (Discovered in the Norfolk Terrier)
  • Muscular Hypertrophy (Double Muscling)
  • Musladin-Lueke Syndrome
  • Myeloperoxidase Deficiency
  • Myotonia Congenita
  • Myotonia Congenita (Discovered in the Labrador Retriever)
  • Myotonia Congenita (Discovered in the Miniature Schnauzer)
  • Myotubular Myopathy
  • Narcolepsy (Discovered in the Dachshund)
  • Narcolepsy (Discovered in the Labrador Retriever)
  • Nemaline Myopathy
  • Neonatal Cerebellar Cortical Degeneration
  • Neonatal Encephalopathy with Seizures
  • Neuroaxonal Dystrophy
  • Neuroaxonal Dystrophy (Discovered in the Papillon)
  • Neuroaxonal Dystrophy (Discovered in the Rottweiler)
  • Neuronal Ceroid Lipofuscinosis 1
  • Neuronal Ceroid Lipofuscinosis 7
  • Neuronal Ceroid Lipofuscinosis 8 (Discovered in the Alpine Dachsbracke)
  • Neuronal Ceroid Lipofuscinosis 8 (Discovered in the Australian Shepherd)
  • Neuronal Ceroid Lipofuscinosis 8 (Discovered in the English Setter)
  • Neuronal Ceroid Lipofuscinosis 8 (Discovered in the Saluki)
  • Neuronal Ceroid Lipofuscinosis 12 (Discovered in the Australian Cattle Dog)
  • Obesity risk (POMC)
  • Osteochondrodysplasia
  • Osteochondromatosis (Discovered in the American Staffordshire Terrier)
  • Osteogenesis Imperfecta (Discovered in the Beagle)
  • Osteogenesis Imperfecta (Discovered in the Dachshund)
  • P2RY12-associated Bleeding Disorder
  • Paroxysmal Dyskinesia
  • Persistent Müllerian Duct Syndrome
  • Phosphofructokinase Deficiency
  • Polycystic Kidney Disease
  • Prekallikrein Deficiency
  • Primary Ciliary Dyskinesia
  • Primary Ciliary Dyskinesia (Discovered in the Alaskan Malamute)
  • Primary Lens Luxation
  • Primary Open Angle Glaucoma (Discovered in Basset Fauve de Bretagne)
  • Primary Open Angle Glaucoma (Discovered in Petit Basset Griffon Vendeen)
  • Primary Open Angle Glaucoma and Lens Luxation (Discovered in Chinese Shar-Pei)
  • Progressive Early-Onset Cerebellar Ataxia
  • Progressive Retinal Atrophy (Discovered in the Swedish Vallhund)
  • Progressive Retinal Atrophy (Discovered in the Basenji)
  • Progressive Retinal Atrophy (Discovered in the Golden Retriever - GR-PRA1 variant)
  • Progressive Retinal Atrophy (Discovered in the Lhasa Apso)
  • Progressive Retinal Atrophy (Discovered in the Papillon and Phalène)
  • Progressive Retinal Atrophy (Discovered in the Shetland Sheepdog - BBS2 variant)
  • Progressive Retinal Atrophy (Discovered in the Shetland Sheepdog - CNGA1 variant)
  • Progressive Retinal Atrophy 1 (Discovered in the Italian Greyhound)
  • Progressive Retinal Atrophy Type III
  • Progressive Rod Cone Degeneration (prcd-PRA)
  • Protein Losing Nephropathy
  • Pyruvate Dehydrogenase Phosphatase 1 Deficiency
  • Pyruvate Kinase Deficiency (Discovered in the Basenji)
  • Pyruvate Kinase Deficiency (Discovered in the Beagle)
  • Pyruvate Kinase Deficiency (Discovered in the Pug)
  • Pyruvate Kinase Deficiency (Discovered in the West Highland White Terrier)
  • QT Syndrome
  • Renal Cystadenocarcinoma and Nodular Dermatofibrosis
  • Rod-Cone Dysplasia 1
  • Rod-Cone Dysplasia 1a
  • Rod-Cone Dysplasia 3
  • Sensory Ataxic Neuropathy
  • Sensory Neuropathy
  • Severe Combined Immunodeficiency
  • Severe Combined Immunodeficiency (Discovered in Frisian Water Dogs)
  • Shaking Puppy Syndrome (Discovered in the Border Terrier)
  • Skeletal Dysplasia 2
  • Spinocerebellar Ataxia (Late-Onset Ataxia)
  • Spinocerebellar Ataxia with Myokymia and/or Seizures
  • Spondylocostal Dysostosis
  • Spongy Degeneration with Cerebellar Ataxia
  • Spongy Degeneration with Cerebellar Ataxia (Discovered in Belgian Malinois)
  • Stargardt Disease (Discovered in the Labrador Retriever)
  • Trapped Neutrophil Syndrome
  • Van den Ende-Gupta Syndrome
  • von Willebrand's Disease, type 1
  • von Willebrand's Disease, type 2
  • von Willebrand's Disease, type 3 (Discovered in the Kooiker Hound)
  • von Willebrand's Disease, type 3 (Discovered in the Scottish Terrier)
  • von Willebrand's Disease, type 3 (Discovered in the Shetland Sheepdog)
  • X-Linked Ectodermal Dysplasia
  • X-Linked Hereditary Nephropathy (Discovered in the Navasota Dog)
  • X-Linked Hereditary Nephropathy (Discovered in the Samoyed)
  • X-Linked Myotubular Myopathy
  • X-Linked Progressive Retinal Atrophy 1
  • X-Linked Progressive Retinal Atrophy 2
  • X-Linked Severe Combined Immunodeficiency (Discovered in the Basset Hound)
  • X-Linked Severe Combined Immunodeficiency (Discovered in the Cardigan Welsh Corgi)
  • X-Linked Tremors
  • Xanthinuria (Discovered in a mixed breed dog)
  • Xanthinuria (Discovered in the Cavalier King Charles Spaniel)
  • Xanthinuria (Discovered in the Toy Manchester Terrier)

*Referenced from https://optimal-selection.com/products/optimal-selection-canine

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